- Trials with a EudraCT protocol (30)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (1)
30 result(s) found for: Smooth Muscle.
Displaying page 1 of 2.
EudraCT Number: 2007-006664-29 | Sponsor Protocol Number: cro955 | Start Date*: 2008-02-26 | |||||||||||
Sponsor Name:Imperial College | |||||||||||||
Full Title: The effect of inhaled corticosteroids (ICS) on airway smooth muscle in asthma | |||||||||||||
Medical condition: Asthma is a disease characterised by reversible airways obstruction, bronchial hyper-responsiveness (BHR), and chronic inflammation of the bronchial mucosal lining. Structural changes in the airwa... | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2004-005174-23 | Sponsor Protocol Number: CAVA2Dec04 | Start Date*: 2005-04-11 |
Sponsor Name:NHS Grampian | ||
Full Title: Is smooth muscle mitogenesis down regulated by platelet inactivation with combination antiplatelet therapy after angioplasty for claudication? | ||
Medical condition: Intermittent claudication = stenosis of superficial femoral artery requiring percutaneous angioplasty | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2016-003509-33 | Sponsor Protocol Number: RECONSTRUCT | Start Date*: 2016-11-30 | |||||||||||
Sponsor Name:Lungemedicinsk Forskningsenhed, Bispebjerg Hospital | |||||||||||||
Full Title: The RECONSTRUCT study Reconstructing Disease Mechanisms in Asthma | |||||||||||||
Medical condition: Asthma | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2006-003075-12 | Sponsor Protocol Number: 290478 | Start Date*: Information not available in EudraCT |
Sponsor Name:Department Of Paediatric Cardiology | ||
Full Title: Effect of carvedilol on left ventricular systolic and diastolic function and the neurohormonal axis in patients with Duchenne muscular dystrophy and left ventricular dysfunction. | ||
Medical condition: Duchenne muscular dystrophy is an X-linked inherited disorder which primarily affects skeletal muscle through a mutation in dystrophin which maps to the long arm of the X chromosome (Xp21). Patient... | ||
Disease: | ||
Population Age: Children, Adolescents, Under 18 | Gender: Male, Female | |
Trial protocol: IE (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2018-002591-40 | Sponsor Protocol Number: P180501J | Start Date*: 2018-11-26 | |||||||||||
Sponsor Name:ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS | |||||||||||||
Full Title: Evaluation of bronchial remodeling during mepolizumab treatment in severe eosinophilic asthma | |||||||||||||
Medical condition: severe oesinophilic asthma | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2008-002278-37 | Sponsor Protocol Number: panto001 | Start Date*: 2008-08-12 |
Sponsor Name:Johann Wolfgang Goethe Universität | ||
Full Title: Auswirkungen von Pantoprazol auf die myokardiale Kontraktilität bei Patienten mit Herzinsuffizienz - influence of pantoprazole on human myocardial contractility at patients with congestive heart fa... | ||
Medical condition: Recently literature revealed facts, that show H+/K+ ATPase expression is not limited tot he stomach. H+/K+ ATPase was also found in smooth muscle cells and in other tissues (McCabe, R.D. et al., Am... | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: DE (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2010-023938-23 | Sponsor Protocol Number: Antrorect/02/09 | Start Date*: 2011-01-12 | |||||||||||
Sponsor Name:BRACCO | |||||||||||||
Full Title: Effect of Mesalazine plus nifedipine suppositoires (Antrorect) in functional ano-rectal pain disorders: a pilot randomized double-blind placebo-controlled study. | |||||||||||||
Medical condition: Functional ano-rectal pain disorders | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: IT (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-001216-11 | Sponsor Protocol Number: FISAN-BOT-2017-01 | Start Date*: 2017-04-25 |
Sponsor Name:Dra. A. Teresa Calderón Duque | ||
Full Title: Usefulness of botulinum toxin type A in the treatment of chronic anal fissure | ||
Medical condition: Chronic anal fissure | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: ES (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2014-001856-51 | Sponsor Protocol Number: 12.007 | Start Date*: 2014-08-26 | |||||||||||
Sponsor Name:Aleksander Krag | |||||||||||||
Full Title: Anti-fibrotic and molecular aspects of rifaximin in alcoholic liver disease: A randomized placebo controlled clinical trial | |||||||||||||
Medical condition: Liver fibrosis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2022-000513-14 | Sponsor Protocol Number: NBK154/2/2021 | Start Date*: 2023-03-08 |
Sponsor Name:Medical University of Gdańsk | ||
Full Title: Evaluation of the Efficacy of Valsartan in Slowing Down Aortic Root Dilatation in Children and Young Adults with Marfan-type Heritable Thoracic Aortic Diseases – Valsar-TAD, a randomised, double-b... | ||
Medical condition: Marfan Syndrome Diseases related to Marfan syndrome (rare diseases with aneurysms of the thoracic aorta and dissection of the aorta), among others: Loeys-Dietz syndrome, Vascular type of Ehlers-Da... | ||
Disease: | ||
Population Age: Children, Adolescents, Under 18, Adults | Gender: Male, Female | |
Trial protocol: PL (Ongoing) | ||
Trial results: (No results available) |
EudraCT Number: 2006-004419-24 | Sponsor Protocol Number: RHMMED0687 | Start Date*: 2007-03-16 | |||||||||||
Sponsor Name:Southampton University Hospitals Trust (R&D) | |||||||||||||
Full Title: The Use of Sulfasalazine as an Anti-fibrotic in Acute Alcoholic Hepatitis | |||||||||||||
Medical condition: Acute Alcoholic Hepatitis | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2009-012676-27 | Sponsor Protocol Number: FemExp-I | Start Date*: 2010-01-24 | ||||||||||||||||
Sponsor Name:Wallenberg laboratory | ||||||||||||||||||
Full Title: Femoral-Express-I | ||||||||||||||||||
Medical condition: Peripheral artery disease. Patients due for by-pass surgery of lower extremity arteries. | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: SE (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-003730-25 | Sponsor Protocol Number: SBT20-102 | Start Date*: 2017-02-14 | |||||||||||
Sponsor Name:Stealth Bio Therapeutics Inc | |||||||||||||
Full Title: A Two Part Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of SBT-020 in Patients with Early Stage Huntington’s Disease. | |||||||||||||
Medical condition: Huntington's Disease | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: NL (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2020-000177-25 | Sponsor Protocol Number: ATA129-EBV-205 | Start Date*: 2021-01-04 | |||||||||||
Sponsor Name:Atara Biotherapeutics, Inc. | |||||||||||||
Full Title: An Open-label, Single-arm, Multicohort, Phase 2 Study to Assess the Efficacy and Safety of Tabelecleucel in Subjects with Epstein-Barr Virus-associated Diseases | |||||||||||||
Medical condition: • EBV+ primary imunodeficiency lymphoproliferative disease (LPD) • EBV+ LPD in the setting of acquired (non-congenital) immunodeficiency • EBV+ post-transplant LPD involving the central nervous ... | |||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: FR (Ongoing) AT (Ongoing) BE (Ongoing) IT (Ongoing) ES (Ongoing) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2005-000841-12 | Sponsor Protocol Number: 215.1364 | Start Date*: Information not available in EudraCT | |||||||||||
Sponsor Name:Boehringer Ingelheim Pharma GmbH & Co. KG | |||||||||||||
Full Title: A randomised open label, six way, cross-over scintigraphic evaluation of the effect of inspiratory flow rate on lung and oropharyngeal deposition with the Respimat(R) inhaler vs a Metered Dose Inha... | |||||||||||||
Medical condition: Chronic Obstructive Pulmonary Disease (COPD) is characterised by airflow limitation and bronchial inflammation. Clinically, COPD is characterised by progressive dyspnoea on exertion and intermitten... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: DE (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2006-005361-19 | Sponsor Protocol Number: 123-2006 | Start Date*: 2007-03-09 | |||||||||||
Sponsor Name:St Georges Hospital | |||||||||||||
Full Title: Evaluation of the efficacy of the dual endothelin 1 receptor antagonist Bosentan in the treatment of Pulmonary Hypertension secondary to Chronic Obstructive Pulmonary Disease and in the treatment o... | |||||||||||||
Medical condition: Pulmonary Hypertension secondary to Chronic Obstructive Pulmonary Disease and secondary to Sarcoid Patients devolop pulmonary hypertension for various reasons, two common causes are Chronic Obstru... | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2017-003258-18 | Sponsor Protocol Number: DOMINO | Start Date*: 2018-03-26 |
Sponsor Name:University Hospital Leuven | ||
Full Title: A randomized controlled trial to evaluate the short-term efficacy and long-term health economic impact of a dietary intervention compared to pharmacotherapy with a musculotropic spasmolytic agent f... | ||
Medical condition: Irritable Bowel Syndrome (IBS); relief of abdominal pain, distension and motility disorders characterised by smooth muscle spasm. | ||
Disease: | ||
Population Age: Adults | Gender: Male, Female | |
Trial protocol: BE (Completed) | ||
Trial results: View results |
EudraCT Number: 2015-005542-56 | Sponsor Protocol Number: ESR-15-10870 | Start Date*: 2016-04-29 | |||||||||||
Sponsor Name:Copenhagen University Hospital Bispebjerg | |||||||||||||
Full Title: Effects of anti-TSLP on airway hyperresponsiveness and mast cell phenotype in asthma - A randomized double-blind, placebo-controlled trial of MEDI9929 The UPSTREAM study | |||||||||||||
Medical condition: Asthma | |||||||||||||
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Population Age: Adults | Gender: Male, Female | ||||||||||||
Trial protocol: DK (Completed) | |||||||||||||
Trial results: View results |
EudraCT Number: 2008-007455-26 | Sponsor Protocol Number: GS-US-235-0101 | Start Date*: 2010-01-21 | |||||||||||
Sponsor Name:Gilead Sciences, Inc. | |||||||||||||
Full Title: A Phase 2, Randomized, Double-blind, Placebo-controlled, Multicenter, Dose-ranging Study of Cicletanine in Subjects with Pulmonary Arterial Hypertension | |||||||||||||
Medical condition: Pulmonary hypertension (PH) is a serious and life-threatening disease of the pulmonary vasculature, characterized by profound vasoconstriction and an abnormal proliferation of smooth muscle cells i... | |||||||||||||
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Population Age: Adolescents, Under 18, Adults | Gender: Male, Female | ||||||||||||
Trial protocol: AT (Prematurely Ended) DE (Prematurely Ended) BE (Prematurely Ended) GB (Prematurely Ended) ES (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2012-000036-26 | Sponsor Protocol Number: PGL11-006 | Start Date*: 2012-12-20 | |||||||||||
Sponsor Name:PregLem S.A. | |||||||||||||
Full Title: A Phase III, multicentre, randomized, double-blind clinical study, investigating the efficacy and safety of repeated 12-week courses of daily 5mg or 10mg doses of PGL4001 for the long-term manageme... | |||||||||||||
Medical condition: Uterine myomas are benign, monoclonal, hormone-sensitive, smooth muscle tumours of the uterus. They are the most common tumour of the female reproductive tract in pre-menopausal women and mostly ... | |||||||||||||
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Population Age: Adults | Gender: Female | ||||||||||||
Trial protocol: DE (Completed) BE (Completed) HU (Completed) GB (Completed) CZ (Completed) LV (Completed) LT (Completed) PL (Prematurely Ended) IT (Completed) | |||||||||||||
Trial results: (No results available) |
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